Introduction to melatonin?
2022-12-03
Melatonin (MT) is one of the hormones secreted by the pineal gland of the brain. Melatonin belongs to indole heterocyclic compounds, its chemical name is N-acetyl-5 methoxytryptamine, also known as pineal gland, melatonin, melatonin.
After melatonin is synthesized, it is stored in the pineal body, and the sympathetic nerve excites the pineal gland cells to release melatonin. The secretion of melatonin has an obvious circadian rhythm, the secretion is suppressed during the day, and the secretion is active at night.
Melatonin can inhibit the hypothalamus-pituitary-gonadal axis, reduce the content of gonadotropin-releasing hormone, gonadotropin, luteinizing hormone and follicular estrogen, and can directly act on the gonads, reducing androgen, estrogen and progesterone content. In addition, MT has strong neuroendocrine immunomodulatory activity and free radical scavenging antioxidant capacity, which may become a new method and approach for antiviral treatment. MT is finally metabolized in the liver, and liver cell damage can affect the level of MT in the body [1-2].
After melatonin is synthesized, it is stored in the pineal body, and the sympathetic nerve excites the pineal gland cells to release melatonin. The secretion of melatonin has an obvious circadian rhythm, the secretion is suppressed during the day, and the secretion is active at night.
Melatonin can inhibit the hypothalamus-pituitary-gonadal axis, reduce the content of gonadotropin-releasing hormone, gonadotropin, luteinizing hormone and follicular estrogen, and can directly act on the gonads, reducing androgen, estrogen and progesterone content. In addition, MT has strong neuroendocrine immunomodulatory activity and free radical scavenging antioxidant capacity, which may become a new method and approach for antiviral treatment. MT is finally metabolized in the liver, and liver cell damage can affect the level of MT in the body [1-2].
